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We also did not measure brain levels of glutamate or inhibitory GABA, which are neuro-transmitters known to be impacted by the ketogenic diet in various animal models

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10.1080/19393210.2015.1094829 [PubMed: 26406785] [CrossRef] Jatho A, Cambia JM, Myung SK (2021)

Compared to NXY-059 and LPBNAH, STAZN is highly lipophilic and has been shown to cross the BBB (it reached a plasma concentration of 2.5% in the forebrain within 23 h after intravenous administration) (Ley et al., 2005)

Thus, a significant repartitioning of S from glutathione synthesis into protein translation is detected, driving an increase of protein S in the sir1 cad2 mutants and alleviating growth inhibition by the sensor kinase Target of Rapamycin (TOR

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