oxidative phosphorylation and glutathione The ascorbate–glutathione cycle coming of age Free Radicals, Glutathione, Superoxide NADPH

and caspase apoptotic pathways [268,280,283]

doi:10.1016/j.steroids.2011.12.001 Thavaraputta S, Dennis JA, Laoveeravat P, Nugent K, Rivas AM

5.3 Remodeling of the immune microenvironment In the immune combination strategy to address gemcitabine resistance, CD40 agonist activation of antigen presentation and oncolytic virus-induced viral mimicry to enhance immunogenic cell death (ICD) are two key directions, which can enhance the efficacy of chemotherapy and reverse resistance by reshaping the immune microenvironment: CD40 agonists (such as Selicrelumab) promote tumor antigen presentation and T cell activation by activating CD40 receptors on the surface of dendritic cells (Vonderheide, 2020), and form an antigen release-presentation-response closed loop when combined with gemcitabine

Shift of the cellular oxidation-reduction potential in neural cells expressing Bcl-2

They keep their glutathione content, whether raw or cooked

(2020) conducted an experiment using clonal and human -cells to examine the effect of AC on -cells under basal and stress conditions