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major components of reward circuitry in addiction of which nicotine enhances through this pathway ( It has been posed that nicotine leads to increases in dopamine levels within prefrontal regions through direct and indirect (GABA and glutamate influences) enhancement of dopaminergic activity that makes up for the lowered dopamine D1 stimulation and ensuing cognitive deficits observed in SZ (103)

The largest study to date, conducted by Cochrane, has shown that E-Cigarettes are a more effective way to quit smoking (6)

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The effect size is similar to NRT monotherapy

Health Risks of Just a Few Cigarettes a Day Light smokers face: 9 times greater risk of dying from lung cancer 3 times greater risk of dying from cardiovascular disease 20% more likelihood of developing chronic bronchitis Your body cant tolerate tobacco