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This distinction is particularly relevant in adolescents, whose developing cardiovascular and nervous systems may be more susceptible to nicotines hemodynamic and neurochemical effects (7)

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PMID 26466050

The risks of nicotine in the doses ingested with e-cigarettes are small, and certainly much much less than the risks associated with inhaling tobacco smoke. But Becky Freeman, a tobacco control expert at the University of Sydney, says supporting e-cigarettes with the current evidence is irresponsible