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Downregulation of CAV1 reduces the levels of GPX4 and FTH1, increases ROS and Fe 2+ concentrations, promotes ferroptosis, and reduces cancer cell migration and invasion, 171 suggesting that the regulatory pathways of CAV1 and ferroptosis may be potential targets for diagnosis and combination therapy strategies in patients with HNSCC

(2019) 364:l1025

will be highly sensitive to ferroptosis in result of GPX4 inactivation

Hepatol (Balt, Md)

Although a preliminary global regulatory framework for BFRs has been established, significant deficiencies persist

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