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In the setting of decreased volume, PGI2, helps maintain renal blood flow by counteracting other vasoconstrictive autocoids

Thats because vitamin B12 is bound to protein and can only be released by digestive substances in the stomach (hydrochloric acid and gastric protease) to be absorbed

Production of this publication has been made possible through a financial contribution from the Ontario Ministry of Health, the Public Health Agency of Canada and Health Canadas Substance Use and Addictions Program