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(Female smokers didnt switch to the same extent, which illustrates that price differentials alone are not always sufficient to achieve public health goals.) This strategy has not been embraced in the United States, where prohibition-minded lawmakers, lobbyists, philanthropists and organizations operate a piecemeal tobacco control agenda that ignores harm reduction in favor of a myopic focus on the youth vaping epidemic, despite the fact that youth vaping rates are falling

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Investigation showed that a route via what is now known as Arthur's Pass was the best option, and in 1866 a road over the pass to Hokitika was opened

As cannabis use continues to grow in legality and access across the U.S., practitioners and clinicians need to remember to assess cannabis use at each patient encounter in order to have a non-judgmental, shared decision conversation about potential cardiovascular risks and ways to reduce those risks. Co-authors, disclosures and funding sources are listed in the manuscript