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The mycelia from our genetically engineered strains, which expressed HA-Ntp1 and the truncated variants HA- ntp1 285708 , HA- ntp1 417708 , and HA- ntp1 589708 , were frozen and disrupted using RIPA buffer to extract total protein

Histological analysis showed that FOXO4-DRI treatment improved the testicular microenvironment, leading to thicker seminiferous epithelia, increased spermatogenic cells, and more mature spermatozoa in the central lumen

Abbreviation List ACTH, Adrenocorticotropin hormone ARE, Antioxidant response element ART, Assisted reproductive technology CAT, Catalase CC, Clomiphene citrate COVID-19, Coronavirus disease 2019 CRH, Corticotropin-releasing hormone GnRH, Gonadotropin releasing hormone GPx, Glutathione peroxidase H2O2, Hydrogen peroxide HPA, Hypothalamic-pituitary-adrenal HPG, Hypothalamic-pituitary-gonadal IBS, Irritable bowel syndrome IVF, In vitro fertilization LH, Luteinizing hormone MMP, Mitochondria membrane potential nAChR, Nicotinic acetylcholine receptors NF-B, Nuclear transcription factor-kappa B Nrf2, Nuclear factor erythroid 2-related factor 2 OS, Oxidative stress PCOS, Polycystic ovarian syndrome POI, Premature ovarian insufficiency ROS, Reactive oxygen species SOD, Superoxide dismutase References [1] India Today

It happens when body iron stores drop too low to support normal red blood cell production

10.1016/j.envexpbot.2021.104736 50 LivakK

Journal of Global Health 2022