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Nicotines potential to induce endothelial dysfunction, oxidative stress, and inflammation suggests a plausible role in accelerating atherogenesis (9, 27)

Previous studies have confirmed that Nrf2 pathway regulates more than 500 genes, including genes that regulate oxidative stress (GCL), inflammation (NF-B), apoptosis (Bcl-2 and Bax), and autophagy (p62) [52]

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Chlamydia infection in the mouth and throat can also be passed on to a partners genitals but cannot be passed on by kissing or non-sexual contact