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Headache Headaches occur due to: 20-30% reduction in GABA levels at the start of the process [22] Dehydration and Pressurenatriuresis: blood pressure rises of 20-30mmHg followed quickly by blood pressure reductions during detox trigger Pressurenatriuresis and increased urination (3-4 litres per day) [23] The excessive release of Corticotropin-Releasing Factor (CRF) during cessation activates mast cells and signals vasodilation [24] Psychological and emotional symptoms Fear of addiction treatment - previous negative experiences may lead to a fear of repeating symptoms, causing continued alcohol abuse Depression and anxiety - 63.8% of those detoxing are suffering from depression, particularly drinking to cope patterns have been used [25] Guilt - for past behaviour and actions towards family and friends Symptoms - How Long

Several studies have also reported a negative correlation between the intensity of smoking and reduced olfactory function

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