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In the clinical practice, many JHS/EDS-HT patients reach the correct diagnosis after dozens of consultations, as well as costly and invasive/ineffective diagnostic procedures

One concern is the potential for drug interactions

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Among them there are (i) the risk of anesthesia-induced hypotension facilitated by dysautonomia, (ii) meningeal fragility complicating in cerebrospinal fluid hypotension in case of epi/peridural anesthesia, (iii) proneness to pelvic prolapse after episiotomy, and (iv) an apparently increased rate of suture dehiscence and minor hemorrhages after surgery

It should be noted that the production of "Chunghwa" cigarettes was treated as a political task at the time, and the company leadership attached great importance to it

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