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The promotion of renal-related inflammatory mechanisms occurs through TMAO activating NLRP3 inflammasomes and NF-B signal transduction, with NF-B playing a role in the DKD process by promoting vascular inflammation and oxidative stress, becoming a potential pathogenic mechanism in DKD (Huang et al., 2023) (Figure 10A)

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Vitamin C Intake and Pancreatic Cancer Risk: A Meta-Analysis of Published Case-Control and Cohort Studies