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Prescription and administration: Once B12 deficiency is confirmed, GPs prescribe hydroxocobalamin injections according to standardised protocols: Standard loading regimen: 1mg intramuscularly three times weekly for two weeks Neurological involvement: 1mg intramuscularly on alternate days until no further improvement Maintenance therapy: 1mg every three months for life in pernicious anaemia or malabsorption conditions (or every two months if there was neurological involvement) Injections are typically administered by practice nurses at GP surgeries

Applying extracellular vesicles based therapeutics in clinical trials - an ISEV position paper

Sustainable therapies by engineered bacteria

Genetic variation in gpbar1 predisposes to quantitative changes in colonic transit and bile acid excretion

The quality and origin of water determine the treatment process, which may include filtration, softening, chemical treatment, etc

doi:10.1016/j.acuro.2013.09.014