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Smoking intensity (pack/day) is a better measure than pack-years or smoking status for modeling cardiovascular disease outcomes

Primary research encompassed over 55 structured interviews conducted in 2024-2025 with e-cigarette brand managers, vape specialty retail buyers, regulatory affairs directors at tobacco multinationals, ASH (Action on Smoking and Health) policy specialists, FDA Center for Tobacco Products analysts, and equity analysts covering tobacco and alternative nicotine sectors

It's unclear whether smokers will find the low-smoke and -ash benefits desirable enough to justify learning an entirely new smoking ritual

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