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doi: 10.1007/s00122-002-1123-x

Host interactions have been shown to induce persister formation in numerous pathogens, with the production of reactive oxygen and nitrogen species heavily implicated in the collapse of bacterial metabolic activity and entry into an antibiotic-tolerant state

Depending on metabolic conditions, the liver can either take up or produce glucose The liver possesses glucose-6-phosphatase, which permits the release of free glucose to the blood

Most healthcare providers recommend starting with a single treatment to assess your response and tolerance