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Insulin-like Growth Factor-1 (IGF-1) is a naturally occurring polypeptide hormone consisting of 70 amino acids and plays a central role in cellular growth signalling, metabolic regulation, and tissue development pathways

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B12 supplements contain only cobalamin, typically in doses from 50 to 1,000+ micrograms, used for confirmed or suspected B12 deficiency

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However if they persist for a period it's advisable to seek advice, from your doctor