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Key pathological features include: Bronchoconstriction: Smooth muscle contraction in response to allergens, irritants, cold air, exercise

"Unequivocal evidence would require a randomized controlled trial, but this would be unethical." Still, one expert noted that while the study can't prove that cannabis was the cause of bipolar disorder or depression, it adds to growing evidence that the drug is not harmless

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Our suspicion is that they are trying to protect their untaxed cigarette business in the event that the state begins to collect taxes on their sales to non-Indian customers. Bob Hilburger, director of business development for NCD LLC, said he didn't know why the Oneidas decided to purchase the cigarette plant

The study is a cluster-randomized design protocol