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Still during mice influenza infection, changes in gut microbiota composition, reduce the acetate production and affect the bactericidal activity of alveolar macrophages (187) contributing to pulmonary pneumococcal superinfection

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Examples include sequential release systems (e.g., GSH depletion followed by ROS generation), self-sustaining cycles (e.g., catalytic O 2 production to enhance sonodynamic or photodynamic therapy), or conditionally activated systems (e.g., hypoxia-triggered prodrug activation) (155, 166)