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Formulations with higher trehalose content exhibited lower mobility, consistent with a more rigid amorphous matrix

Notably, the mechanism of action is currently unknown, and its concentration may be a major factor in its inhibitory effect (Shinge et al., 2022)

References Mission Therapeutics Ltd

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The concurrent proton flow, from the mitochondrial matrix to the intermembrane space, generates the intermembrane proton gradients, which are essential for oxidative phosphorylation and subsequent adenosine triphosphate (ATP) synthesis [5]

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