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In addition, the complexity of the pathological mechanisms of some diseases is unclear, and the controversial relationship between ferroptosis and other modes of cell death is also an issue that needs to be addressed for the application of ferroptosis inhibitors to disease

coli strain XL1-Blue was transformed with the according pQE30 plasmid for the expression of wild-type and mutant SCGRX7 and HSGRX5 C122S

Chytrova G, Ying Z, Gomez-Pinilla F (2010) Exercise contributes to the effects of DHA dietary supplementation by acting on membrane-related synaptic systems

doi: 10.3389/fmicb.2023.1130208 73

Both recycling and transcytosis rely on strict pH dependent Fc binding to FcRn, with binding at acidic (pH 6.55.5) and release or no binding at neutral pH 21,22