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Adipose tissue depot-specific differences in adipocyte apolipoprotein E expression

507 Therapeutic prospect in halting CS Given the significant impact of CS on disease pathology, there has been ongoing research into strategies aimed at quick diagnosis and therapy targeting of CS

Despite low GSH levels, GSSP was significantly elevated in CF children with pulmonary infections, correlating with increased bronchiectasis risk

380,381 Hypercytokinemia induced by Th-17 was identified as an initial host response in severe cases of H1N1 infection in 2009

Collectively, these OFF-to-ON switching strategies illustrate therapeutic approaches in which GSH acts as a biological trigger for selective activation of cytotoxic agents in the GSH-rich tumor microenvironment

In a double-blind, placebo-controlled study, individuals taking 200 mg/daily of Pycnogenol had significant improvements in joint discomfort, function, and performance on a treadmill