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Specifically, among those with remitted substance use disorders who were smokers at the beginning of the study, more than 1 in 10 (11 percent) who continued smoking three years later relapsed to illicit substance use three years later, while only 8 percent of those who had quit smoking and 6.5 percent of never-smokers relapsed to substance use

In a large British study of ex-smokers in the 1980s, before the advent of pharmacotherapy, 53% of the ex-smokers said that it was "not at all difficult" to stop, 27% said it was "fairly difficult", and the remaining 20% found it very difficult

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But even the woman who brings Beth to life, actress Kelly Reilly, has her limits when it comes to playing the character

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