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The dossier presents a systematic review of the recent literature (20192024) on intravenous anti-aging therapy with NAD and glutathione, with the aim of providing an evidence-based overview for aesthetic physicians, endocrinologists and specialists in regenerative medicine

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It is largely distributed in natural plants, such as Myricaceae, Vitaceae, Leguminosae, Primulaceae, Rosaceae, Ericaceae, Fagaceae, and Compositae, but it is also present in berries, fruits, vegetables, honey, and red wine [54,55,56,57]

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ALOX15 KD normalized the intracellular GSH ( P = 0.003), while chemical inhibition of 15LO1 had a marginal, but insignificant effect ( P = 0.066)