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The calculation is based on the total absolute difference between the pixel value and the values of the neighboring pixels

Because smoking can alter the compositon of the gut microbiome, lessen response to TNF-alpha inhibitors, and increase AS severity, smokers and nonsmokers were analyzed separately

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he quoted Rabbi Joseph Escapa as coinciding in this view, though he thought it unwise to enforce a generally accepted law

Opening track Into the Blue finds reflection in settling with, and recognising, negative emotions and waiting for a window to open beyond the darkness