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The metabolites of low-nicotine cigarettes were detected by two-way hierarchical clustering performed based on the expression levels of differential metabolites

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The durable nature of quality vaping devices enables extended usage periods spanning years with proper maintenance, distributing capital costs across thousands of usage sessions while variable operational expenses remain constrained to e-liquid replenishment and occasional component replacement

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The aerosol mist from vaping devices can act like smoke, disrupting the light beans in optical smoke alarms, causing nuisance alarms with no smoke or fire present and possible damage to the alarm

Future Directions Given the points above, future research should prioritize long-term, longitudinal human studies with large and diverse populations, consider the rapidly changing landscape of e-cigarette products, and focus on comprehensive exposure assessments to elucidate the potential risks of vaping, particularly concerning lung cancer