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J Neurosci Res 59:421429 Zhou Q, Anderson DJ (2002) The bHLH transcription factors Olig2 and Olig1 couple neuronal and glial subtype specification

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Initially, a toxic iron reaction is associated with an excess of stored iron (25), which can accelerate cerebral tissue oxidation by increasing oxygen radical generation (26)

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Even though amputations in patients with diabetes are multifactorial, neuropathy is clearly one of the major contributors to their occurrence