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Figure 1 Despite recent progress, the mechanistic links between circadian rhythms and BBB dynamics remain incompletely understood, and current animal models are limited by interspecies physiological differences

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they describe investigational findings and do not represent therapeutic outcomes or approved indications in humans

Brain-associated innate immune cells in health and homeostasis The CNS harbors distinct innate immune populations, notably BAMs and innate lymphocytes

Future research endeavors should focus on further elucidating the molecular mechanisms behind the varying effects of different HA sizes, which will undoubtedly enhance our understanding and utilization of this remarkable molecule

Chashmniam S, Mirhafez SR, Dehabeh M, Hariri M, Azimi Nezhad M, Nobakht MGBF