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Oral administration of ciprofloxacin during organogenesis at doses up to 100 mg/kg to pregnant mice and rats, and up to 30 mg/kg to pregnant rabbits did not cause fetal malformations (see Data)

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West Germany only began re-examining the issue of protection for non-smokers in the early seventies, with an important debate held on 18 June 1974 in the Bundestag in Bonn