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Among these, biotic stresses involve significant losses in agricultural yield and food production, affecting the global economy (Pereira, 1989

We and others have shown that short-term glucose stimulation, which increases prooxidant status via cytoplasmic NOX4, is necessary for efficient insulin secretion, whereas long-term stimulation, which tends to induce oxidative stress, can lead to the development of T2D ( The most important, but still technically elusive problem in redox signaling is the compartmentalization of redox status

Our previous study reported that the treatment of 10 g/Kg/day BPC 157 could accelerate the recovery of blood flow in the ischemic muscle of the rat hind limb as detected by laser Doppler scanning

About this article Cite this article Rahman, M.M., Islam, M.B., Biswas, M

doi: 10.1016/j.drudis.2022.03.003 5 SuzukiKMatsumaruYTakeuchiMMorimotoMKanazawaRTakayamaYet al