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These changes put the diaphragm at a mechanical disadvantage, resulting in a reduced ability of the diaphragm to generate flow and pressure, increasing respiratory work, and causing diaphragmatic fatigue ( In addition to the negative changes, there are some positive adaptive structural changes in the diaphragm of patients with COPD

Bradfords law, which describes the distribution of articles in scientific journals (75) (Figure 4b), where the gray areas represent core journals in the field

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Role of UPF1 in lncRNA-HEIH regulation for hepatocellular carcinoma therapy

and 32%, respectively