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In malignant cells reactive oxygen species (hydroxyl radicals, superoxide radicals, hydrogen peroxide and singlet oxygen) directly influence the nuclear transcription factor and change the expression of Bcl-2, Bax and p53

Artemisinin and its derivatives can induce Ferroptosis by increasing reactive oxygen species

Grace Hamel, Hermon

In contrast, use of calcium-ethylenediaminetetraacetic acid (CaEDTA), a non-specific chelator that does not redox-silence iron, caused a minor (undisclosed) increase in lifespan 21

Insulin-like growth factor-1 inhibits mature oligodendrocyte apoptosis during primary demyelination

Glutathione Oxidative stress and inflammation has been associated with reduced egg and sperm quality