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This manuscript reflects the authors points of view and thoughts based on the research findings, and the information, conclusions, and recommendations presented are not to be misconstrued as those of the DOH

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This review aims to discuss the significant effect that E-cig use has on the BC tumor microenvironment, which ultimately leads to enhanced tumor malignancy and metastasis, with an emphasis on the impact that E-cig use has on the crosstalk between cancer and immune cells, as well as the potential underlying mechanisms that drive this aggressive phenotype of BC

A., Trihopoulos, D

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