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Although there is no consensus regarding the increased activation of nicotinamide adenine dinucleotide phosphate oxidase by smoking, xanthine oxidase, an ROS-producing system, is activated by smoking

Benowitz adds that citing the study in campaigns encouraging older smokers to quit or switch to a non-combusted form of nicotine, such as e-cigarettes or nicotine pouches, could be a good next step

"It's not an ice cream table

Digit preference and avoidance in the age statistics of some recent African censuses: Some patterns and correlates

Hence, tailored prevention toward patients is necessary but not sufficient per se to reduce smoking