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Long-term animal studies for assessment of toxicity and carcinogenesis are not ideal models because of the requirement for long-term intensive smoke exposure, the length of time required to induce visible tumors, and the lack of an established robust animal model for cigarette smoke-mediated carcinogenesis

So we all are already paying that tax

And who will be left standing at the end of this bureaucratic nightmare

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Finally, the combustion of cigarette paper during CC smoking contributes to the emissions of sulphates, chlorides, and nitrates