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But it can also cause acute increases in serotonin synthesis and turnover

JAMA 321(19):19261927 Corcoran C, Jacobs TF (2021) Metformin

Surgical and nutritional outcomes of laparoscopic proximal gastrectomy versus total gastrectomy: a meta-analysis

Upon severe peripheral nerve injuries, drastic disturbance in both physical barriers and physiological/immune homeostasis happens in the injured nerve microenvironment characterized by excessive inflammation, dysregulated metabolism, abnormal vascularization, and disrupted transduction of electric signals, etc., while such imbalanced neuronal microenvironment has dramatic negative effects on the regeneration and functional recovery of injured nerves [62]