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Silva et al., 2023)

N.WangJ.et al (2011)

10.1136/svn-2023-002614 68 QiuM.ZongJ.-B.HeQ.-W.LiuY.-X.WanY.LiM.et al (2022)

Oral GLN dramatically increases the expression of the pro-apoptotic factor Bad and suppresses the expression of Bcl-2, according to the detection of the apoptosis pathway

Chromatin accessibility is regulated by epigenetic modifications, including histone methylation, histone acetylation, and DNA methylation, among which histone modifications are well-established drivers of inflammatory memory

Two regimensguadecitabine combined with pembrolizumab (NCT02901899), and atezolizumab combined with guadecitabine and the CDX-1401 vaccine (NCT03206047)have completed enrollment, with results pending release