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To conclude, and accordingly to the data summarized here, melatonin is considered a potent molecule that has received increasing attention in the management of a large variety of diseases with an inflammatory etiology 7,70,71,72,73,79 (Fig

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(2) Administrating multiple immunosuppressive agents to individual patients

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El-Tarabily, [email protected] These authors have contributed equally to this work and share first authorship This article was submitted to Nutrition and Metabolism, a section of the journal Frontiers in Nutrition Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Results: MLE inhibited calcium oxalate crystal formation, reduced MDA levels, increased SOD activity, and prevented tubular epithelial cell degeneration, epithelial necrosis, and interstitial inflammation in the kidneys