E-cigarettes often contain nicotine the same drug present in regular cigarettes which means vaping can become addictive and impact the brain

Behavioral Changes Big shifts in personality or mood Being secretive about where they go or who theyre with Getting defensive over small questions Losing interest in hobbies or things they used to care about Trouble at work or school Unusual sleep patterns or eating habits that go beyond the typical changes in adolescence Physical Signs Red or bloodshot eyes, or pupils that seem unusually large or small Frequent nosebleeds or a constantly runny nose (without being sick) Poor hygiene or changes in grooming Unexplained injuries, bruises, or marks Shaky hands, slurred speech, or other changes in coordination A persistent cough or raspy voice Social and Financial Signs Hanging out with a new crowd they wont talk about Missing money or valuables Financial struggles or suddenly asking for money Pulling away from close friends or family Legal trouble or risky decisions No single sign means something is definitely wrong

Panlobular Emphysema (PLE) Affects all areas of the lungs evenly, often linked with alpha-1 antitrypsin deficiency
This results in slower healing and an increased risk of infection after wisdom tooth removal
This particular investigation is notable because of the size of the sample and the duration of the investigation
Vol 29 Lyon, France: IARC pp