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The researchers also found differences between Tregs in ME/CFS compared to long Covid.[ref] However, other studies show IL2 is significantly higher in extracellular vesicles in ME/CFS patients.[ref] Related article: IL-2 variants and immune balance Thus, we have the circle of immune system activation causing mitochondrial damage, as well as mitochondrial damage causing immune system activation

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Over the last decade, novel cell death pathways were discovered, including necroptosis, ferroptosis, cuproptosis, etc