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Theoretically, the export of both types substrates is possible from chloroplasts as the transamination (and also deamination reactions) of keto acids could be catalyzed by both chloroplastidic BCAT3 ( in vitro were not successful till now, as the direct measurements of transport of these substrates in artificial membranes is problematic due to higher hydrophobicity of substrates leading to unspecific membrane binding and permeation, which override the specific transport events ( PAPS/PAP ANTIPORTER IN CHLOROPLASTS Along with the BAT5, which exchanges 2-keto acids between chloroplast and the cytoplasm, the chloroplastidic transporter of activated sulfate (PAPS), which is essential for the sulfation of GSLs, flavonols, peptides, and other sulfated compounds in the cytoplasm has been recently identified ( Figures 1 and 2 , transporter 5)

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Calheiros J, Corbo V, Saraiva L

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Free radicals are unstable atoms or molecules generated during normal bodily processes like metabolism and exercise or from environmental toxins such as pollution and cigarette smoke

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The unique aspect of glutathione is the cysteine thiol group (SH) which acts as a reducing agent and can be reversibly oxidized and reduced

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Appl Microbiol Biotechnol 94:13131319 Hara KY, Aoki N, Kobayshi J, Kiriyama K, Nishida K, Araki M, Kondo A (2015) Improvement of oxidized glutathione fermentation by thiol redox metabolism engineering in Saccharomyces cerevisiae

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