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In cholangiocarcinoma, the combination of BET degradation and mTOR inhibition synergistically reduces acetylation of PSAT1-H3K27, inducing PSAT1 downregulation and subsequent SGOC pathway dysfunction [113]

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Neurotoxic effects of environmental contaminantsmeasurements, mechanistic insight, and environmental relevance

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10.1007/s12035-012-8318-1 Mol

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10.1016/j.pathophys.2006.05.007

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The rise in abscisic acid (ABA) levels from 23 to 29.8 ppb though suggests enhanced drought signalling, it indicates that ABA may not have a major role in stress response, rather osmotic adjustment and anti oxidant defense mechanism control drought tolerance

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