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Inflammatory cytokines may be produced by mononuclear cells of the immune system in response to numerous agents, such as microorganisms and their products (e.g., lipopolysaccharide LPS)15,16 as well as some xenobiotics.17 It is postulated that xenobiotics can influence the concentrations of inflammatory cytokines through oxidative stress mechanisms.1820 The experimental and epidemiological data currently available to evaluate the above toxigenic risks of aspartame are insufficient and often unreliable, due to the inadequate planning and conduct of previous experiments

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10.1210/jc.2006-1702 20 JastreboffA

(Flushing and hypotension may occur from too rapid injections by the intravenous route.) Dermatologic: Urticaria, pruritus, purpura, rash, cyanosis

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Measurement of oxidative stress and total antioxidant capacity in hyperthyroid patients following treatment with carbimazole and antioxidant