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We have also reported that NAC does not interfere with the myeloablative effect of Bu in vitro or in animal models, and that it can be considered for SOS prophylaxis during Bu conditioning 21

-Tocopherol prooxidants effect in aqueous media: Increased autoxidation rate of linoleic acid

10.1161/01.CIR.0000138743.09012.93

Moreover, when reacting with free radicals, intracellular lipids can cause oxidative damage and even cell death owing to the production of lipid peroxides

Additionally, BSO increased NGF levels and activated the NGF/TrkA/Akt pathway in striatal neurons

The present study showed MDAs elevation in the I/R group, indicating the cellular damage resulted in testicular ischemia reperfusion, despite a reduction in the treatment groups, PC and PRP/PC, in comparison with the SH group