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Covariates included sociodemographic variables: age, gender(male, female), race (American, White, Black, other), marital status (married/living with a partner, widowed/ divorced/separated/never married), education level (lower than 12th grade/high school graduate or equivalent/some college or AA degree/college graduate or higher), poverty income ratio (PIR) and behavioral factors: smoking status (never, former and current), drinking status (never, former, mild, moderate, heavy), physical activity (yes, no)

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Signal transducer and activator of transcription 3 (STAT3) binds to DNA response elements in the promoters of ferroptosis-related genes (FTH1, SLC7A11, and GPX4) and regulates their expression

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