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My Life My Quit How Nicotine Works Acute and Chronic Effects of Cigarette Smoking. Top: Acute effects of Download Scientific Diagram What Happens When You Smoke? Cigarettes contain nicotine, tar, and carbon monoxide. Short term effects: Increased heart rate Higher blood pressure Reduced oxygen Long term effects: Lung cancer Why flavored vape products may be attractive: Green apple tobacco flavor elicits reward related behavior, upregulates nAChRs on VTA dopamine neurons, and alters midbrain dopamine and GABA neuron function ScienceDirect Nicotine inhibits the VTA to amygdala dopamine pathway to promote anxiety ScienceDirect The Science Behind Nicotine Dependence Haleon HealthPartner
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