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She predicts smoking will have a continuous downward trend

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Authors' contributions AJ conceived of the study, participated in its design and coordination and helped draft the manuscript

Even flicked into the drain they can cause damage in freshwater ecosystems: because nicotine is very water soluble

It can also trigger disorders like erectile dysfunction

A substantial body of research over the past decade has been transformed into the scientific and medical foundation for tobacco harm reduction, the substitution of safer sources of nicotine, including tobacco products, by those smokers who are unable or unwilling to achieve nicotine and tobacco abstinence