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The application of AsA can be used against drought stress in various plant species, such as wheat ( An additional mechanism by which plants increase drought resistance is the accumulation of glutathione, a major antioxidant that conjugates with electrophilic compounds and facilitates peroxide reduction ( G6PDH and six GST genes were upregulated by approximately 2-fold under SD treatment, indicating that soybean can activate the GSH metabolism pathway to scavenge ROS under SD stress

PMCID: PMC3073317

As the sole intracellular LPO-reducing enzyme, the lack of GPX4 results in excessive accumulation of LPO, destabilizing biological membranes, exacerbating oxidative stress, and ultimately promoting ferroptosis (Ursini and Maiorino, 2020)

In a model of irradiation retreatment of the lung (stimulating radiotherapy for lung cancer local recurrence), normal lung tolerance is increased by administration of manganese SOD-PL

(2023) 51:D395402

Anti-Aging Effects The combined antioxidant power of vitamin C and glutathione can help combat signs of aging by reducing oxidative stress and promoting cellular repair