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Nevertheless, by pooling the data, we were able to construct an accurate model based on, respectively, more than 600 and more than 300 PK and PD data points

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AST/Bex also upregulated the expression of ABCA1, LRP1, and/or APOA-I, thereby facilitating cholesterol efflux partially through PPAR/RXR activation, and downregulated cholesterol biosynthesis and esterification

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L.EvansA.et al (2014)

Thirdly, the current study focused on patients with MoCA scores below 26, and future research would benefit from including SCZ patients with minimal cognitive deficits (MoCA 2730) to provide a more comprehensive understanding of the relationship between ferroptosis markers and cognitive function in SCZ