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The addition of NO to GSH would form a thionitroxide which has been implicated as an intermediate in the slow direct oxidation of thiols by NO to form disulfides [8,9]

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doi:10.1038/192047a0

Therefore, the clinical efficacy of these dietary nutritional factors in the treatment of AD needs to be further evaluated in clinical trials

To a stirred solution of 5-fluoro-4-iodo-2-(2,2,2-trifluoroethoxy)pyridine (1.06 g, 3.3 mmol), bis(pinacolato)diboron (1.67 g, 6.6 mmol), PdCl 2 (dppf) (242 mg, 0.33 mmol), and dioxane (11 ml) was added KOAc (0.97 g, 9.9 mmol)