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Zolbetuximab is being proposed to treat patients with locally advanced unresectable or metastatic human epidermal growth factor receptor 2 (HER2)-negative gastric or gastroesophageal junction (GEJ) adenocarcinoma whose tumors are CLDN18.2 positive

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and Pharmacol 271, 109663

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For example, because liver fibrosis is the common outcome for many chronic liver injury conditions, the current available drug-induced fibrosis models or humanized mouse models can present only part of the clinical scenarios